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Kidney Stones


What Are Kidney Stones?

Kidney stones constitute one of the commonest diseases in our country and pain due to kidney stones is known as worse than that of labour pain. In India, approximately 5 -7 million patients suffer from stone disease and at least 1/1000 of Indian population needs hospitalization due to kidney stone disease.

Urinary Stones - Geographical Distribution

The kidney stone disease is widespread particularly in countries with dry, hot climate. These "stone belt regions" of the world are located in countries of Middle East – Dubai, Sharjah, Qatar, Muscat, Abu Dhabi, Saudi Arabia, North Africa, the Mediterranean Regions, North Western state of India and Southern State of USA and areas around the great lakes.

In India, the "stone belt" occupies parts of Maharashtra, Gujarat, Punjab, Haryana, Delhi and Rajasthan. In these regions, the disease is so prevalent that most of the members of a family will suffer from kidney stones sometime in their lives. Removal of Kidney, Ureteric and Bladder stone procedure forms one of the commonest procedures in Urology department of the hospitals in these regions.

What Causes Kidney Stones?

  1. Kidney Stones: can be formed anywhere in the urinary system, like kidney, ureter, and bladder. The process by which the stone formation occurs is Supersaturation of urine.
  2. Hereditery :This may have some role as some people in the same family are more prone to form kidney stones.
  3. Diet : Diet is not a dominating factor. However, if an individual is a stone former the diet rich in calcium, oxalated & uric acid may increase the chances of stone fornation. In normal individual, diet will not play much role. More than the diet; water intake may be more responsible for kidney stone formation.
  4. Water Intake: If an individual is a stone former then an increased intake of water will help him pass small gravels before they become nidus for stone formation. Unfortunately, in stone belt region due to dry climate the water is hard and will infact contribute to the formation of stones, if taken in large quantities.
  5. Medications: Medications like diureteric, excess calcium containing antacids or calcium pills will increase the chances of forming stones.
  6. Other chronic medical illness: Some chronic illness are associated with kidney stone formation specially cystic fibrosis, renal tubular acidosis and inflammatory bowel diseases etc are associated with increased risk of kidney stones formation.

Types Of Urinary Calculi (Urinary Stones)

There are various types of urinary stones, but the most common ones are

  • Calcium oxalate.
  • Uric acid.
  • Struvite.
  • Cystine stones.

Symptoms And Signs:

  • Incidental diagnosis on routine health check-ups.
  • Dull aching pain in the back.
  • Acute colic – This colic pain begins from the flank or the side of mid-back and comes forwards to the groin (from loin to groin). This pain is considered to be worse than labour pain, accompanied by nausea, vomiting and gaseous distension.
  • Urinary tract infection.
  • Increased frequency of urine.
  • Pain and or burning while passing urine.
  • Passage of blood in urine (Haematuria).

Investigations:

  • Physical Examination– to be done to localise the size and nature of pain.
  • Routine urine analysis
    1. Crystals in urine
    2. Blood Cells
    3. Puss cells in urine
  • CBC, Renal Profile
  • Urine for Culture Sensitivity – To rule out UTI and select best antibiotics to treat the infection.
  • USG of KUB– To show the size and swelling (Hydronephrosis) of the kidney and the ureter in obstructive uropathy. It does not give information of function of kidney.
  • Intravenous Urography (IVU) – To detect the size and site of stone along with function of kidney.
  • CT Scan of Abdomen pelvis /CT Urography – with or without oral or intravenous contrast. It also gives density of the renal stones in Hounsfield units (HU). It also gives the function of the kidney.

Stone Work Up:

In a rapid recurrent stone former – The metabolic activity for stone formation can be assessed by following investigations for the prevention of stone formation:

  • Serum Calcium.
  • Serum Phosphorus.
  • Serum Uric acid.
  • 24-hour urinary calcium / 24 hrs urinary uric acid.
  • Stone analysis of the retrieved calculus.

Treatment Of Renal Calculi:

It has been said that "once a kidney stone former, always a kidney stone former". Once a kidney stone has been diagnosed, the choice is between expectant treatment and more aggressive forms of treatment, such as transurethral, percutaneous, or open surgeries or extra corporeal modalities. Although some kidney stones may pass spontaneously and unless complicating conditions arise, surgical intervention may not be necessary. Thus, identification of kidney stones that are likely to pass is of utmost importance.

The primary decision is whether to apply surgical treatment or wait. Removal of kidney stones by any methodology is necessary when there is evidence of:

  • Significant obstruction
  • Progressive deterioration of the kidney
  • Progressive deterioration of the kidney
  • Unremitting pain
  • Stone obstruction an infected kidney requires emergency intervention

Treatment Of Kidney Stones

Extra Corporeal Shock wave Lithotripsy (ESWL) - Extra Corporeal Shock Wave Lithotripsy (ESWL) is a preferred mode of treatment for kidney stones upto 1.5 cm in size. An IVU is done prior to ESWL treatment to confirm the open passage from kidney to bladder for the finer fragment to pass out after a successful ESWL treatment. ESWL machine uses highly focussed sound wave projected from outside the body to break kidney stones. The stone is generally reduced to sand like particles which subsequently passes out in the urine. More than 1.5 cm to 2 cm stones generally requires more than one or two ESWL treatments.

The primary decision is whether to apply surgical treatment or wait. Removal of kidney stones by any methodology is necessary when there is evidence of:

Percutaneous Nephrolithotripsy (PCNL) – Synonyms - Tunnel Surgery, Key Hole surgery for Kidney Stones

PCNL treatment is for a larger stone which are not indicated by ESWL. This procedure is generally done under general anaesthesia, spinal and /or epidural anaesthesia. In this technique the stone is removed by making a small tunnel into the kidney from the back. A fine needle is used to puncture the renal collecting system with the aid of X-ray and/or Ultrasonography, and a guide wire is led into the kidney through the needle. This tract is dilated over the guide wire and a Nephroscope (kidney telescope) is inserted into the pelvis of the kidney. The stones are visualized, fragmented using Swiss Lithoclast and extracted using fine forceps, allowing the kidney to become free of stones at the end of the operation, in the vast majority patients.

This Percutaneous Nephrolithotomy (PCNL) technique is used to treat kidney stones of:

  • Large than 2.5 cms,
  • Staghorn calculus,
  • Calyceal diverticular calculus.